Ahmad Abdullah Mahdeen

Lecturer (Microbiology)

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ORCID: 0009-0001-6706-8988

Details

Ahmad Abdullah Mahdeen is a Lecturer and Researcher in Microbiology at Notre Dame University Bangladesh (NDUB) since July 2025. He holds a B.Sc. and MS in Microbiology from Noakhali Science and Technology University (NSTU), achieving 1st Class 1st in his MS.

He is an interdisciplinary researcher with expertise in immunology, oncology, bioinformatics, genomics, virology, stem cell biology, molecular biology, and astrobiology, with strong experience in both wet lab and computational research. His work includes vaccine, drug, gene therapy, and CAR-T cell design, cancer biomarker analysis, and microbial identification and susceptibility testing involving bacteria, plant extracts, heavy metals, and nanoparticles.

He is recognized for his high impactful research, attention to detail, innovative thinking, and commitment to academic excellence.

Education

• Master of Science (MS) in Microbiology, Noakhali Science and Technology University (NSTU)
• Bachelor of Science (BSc) in Microbiology, Noakhali Science and Technology University (NSTU)
• Higher Secondary Certificate (HSC) in the group of Science, Ideal College
• Secondary School Certificate (SSC) in the group of Science, A.K. High School

Research Publications

2026:

1. Siddiquee, N.H., Sami, M.S.H., Rahman, M.A. et al. Design of a global population-covering multi-epitope mRNA vaccine against Lassa virus using immunoinformatics.
   Journal: Scientific Reports, DOI: https://doi.org/10.1038/s41598-026-36965-6
2. Mahdeen AA, Hossain I, Masum MHU, Rabbi TMF, Islam S (2026) A novel mRNA-based multiepitope vaccine candidate against Cryptosporidium hominis and Cryptosporidium parvum employing reverse-vaccinology and immunoinformatics approaches.
   Journal: PLOS ONE, DOI: https://doi.org/10.1371/journal.pone.0343643
3. Siddiquee NH, Al Mamun MA, Dremit TI, Ullah O, Ritu IJ, Shethe AK, Rochona NP, Tabrez S, Islam J, Mawa J, Shakil S, Mahdeen AA, et al. (2026), Reverse vaccinology and immunoinformatics Approaches Driven designing of a Novel Multi-Epitope mRNA vaccine against Toxoplasma gondii,
   Journal: Human Immunology, DOI: https://doi.org/10.1016/j.humimm.2026.111731

2025:

1. Masum MHU, Lokman SM, Parvin R, Rahman MS, Chowdhury EH, Chamonara K, Chowdhury S, Mahdeen AA, Khatun MM, et al. (2025) Bioactive fungal metabolites as SIRT2 antagonists: A computational quest for cancer treatment.
   Journal: PLOS ONE, DOI: https://doi.org/10.1371/journal.pone.0339474
2. Masum MHU, Khatun MM, Akter F, Parvin R, Mahdeen AA, et al. (2025) Phytochemical inhibitors against MPOXV: Insights from molecular dynamics simulation and pharmacokinetics profile.
   Journal: In Silico Research in Biomedicine, DOI: https://doi.org/10.1016/j.insi.2025.100056
3. Masum MHU, Lokman SM, Parvin R, Rahman MS, Chowdhury EH, Chamonara K, Chowdhury S, Mahdeen AA, Khatun MM et al. (2025) Novel fungal metabolites as dual cholinesterase inhibitors: A computational approach for Alzheimer’s disease therapy.
   Journal: PLOS ONE, DOI: https://doi.org/10.1371/journal.pone.0326219
4. Mahdeen AA, Arpa SH, Hasan MR, Barua L, Ferdous J, Masum MHU, et al. (2025) Next-gen vaccine design: Integrating proteomics and bioinformatics for japanese encephalitis.
   Journal: Computational and Structural Biotechnology Reports,
   DOI: https://doi.org/10.1016/j.csbr.2025.100049
5. Barua A, Masum MdHU, Mahdeen AA. A Reverse Vaccinology and Immunoinformatic Approach for the Designing of a Novel mRNA Vaccine Against Stomach Cancer Targeting the Potent Pathogenic Proteins of Helicobacter pylori.
   Journal: Bioinformatics and Biology Insights,
   DOI: https://doi.org/10.1177/11779322251331104
6. Masum MdHU, Mahdeen AA, Barua A. Revolutionizing Chikungunya Vaccines: mRNA Breakthroughs With Molecular and Immune Simulations.
   Journal: Bioinformatics and Biology Insights,
   DOI: https://doi.org/10.1177/11779322251324859

2024:

1. Masum MHU, Mahdeen AA, Barua L, Parvin R, Heema HP, Ferdous J Developing a chimeric multiepitope vaccine against Nipah virus (NiV) through immunoinformatics, molecular docking and dynamic simulation approaches-,
   Journal: Microbial Pathogenesis, DOI: https://doi.org/10.1016/j.micpath.2024.107098
2. Mahdeen AA, Hossain I, Masum MHU, Islam S, Rabbi TMF, Designing novel multiepitope mRNA vaccine targeting Hendra virus (HeV): An integrative approach utilizing immunoinformatics, reverse vaccinology, and molecular dynamics simulation,
   Journal: PLOS One, DOI: https://doi.org/10.1371/journal.pone.0312239
3. Parvin R, Habib Ullah Masum M, Ferdous J, Mahdeen AA, Shafiqul Islam Khan M (2024) Designing of a chimeric multiepitope vaccine against bancroftian lymphatic filariasis through immunoinformatics approaches.
   Journal: PLOS ONE, DOI: https://doi.org/10.1371/journal.pone.0310398

Conference Articles

2026

1. Akhi Das, Md. Shakib Hossen Shek, Md Nur Alam, Kishor Mazumder, Biswajit Biswas, Noimul Hasan Siddiquee, Ahmad Abdullah Mahdeen, An Immunoinformatics approach to design a novel multiepitope mRNA vaccine for Gallbladder cancer
   Conference name: 1st International Conference on Life Science, Health, and Biotechnology (Life Tech 2026)
2. Lamyea Kabir, Md. Aftabur Rahman, Mohammad Hasan, Hasan Md Saiduzzaman Sourov, Ahmad Abdullah Mahdeen, Integrative In Silico Design of a Multi-Epitope mRNA Vaccine Candidate Targeting Marburg Virus Glycoprotein, Nucleoprotein, and Structural Proteins: A Reverse Vaccinology Approach with Immunoinformatics Validation.
   Conference name: 𝐑𝐒𝐁𝐑𝐔 𝐈𝐧𝐭𝐞𝐫𝐧𝐚𝐭𝐢𝐨𝐧𝐚𝐥 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐒𝐮𝐦𝐦𝐢𝐭 𝟐𝟎𝟐𝟔

2025

1. Ahmad Abdullah Mahdeen, Supantha Rivu, Farjana Afroj, Md. Shahidul Kabir, A Reverse Vaccinology Driven mRNA Vaccine Combating Esophageal Cancer: A Cutting-Edge Approach Through Molecular Docking, Dynamics, and Immune Simulations
   Conference name: ISBM Annual International e-Conference 2025
2. Nusrat Afrin, Ahmad Abdullah Mahdeen, Logon Barua, Sumaia Sultana, Md. Habib Ullah Masum, A reverse-vaccinology based mRNA vaccine for Triple Negative Breast Cancer utilizing Molecular Docking, Dynamic and Immune Simulation
   Conference name: 2nd ISCB RSG Bangladesh Computational Biology Symposium 2025

2024

1. Ahmad Abdullah Mahdeen, Md. Habib Ullah Masum, Abanti Barua Exploitation of Biocomputational Approaches for siRNA-Mediated Gene Silencing of MPOX: A Novel Therapeutic Strategy
   Conference name: 38th BSM ANNUAL CONFERENCE.
2. Abanti Barua, Ahmad Abdullah Mahdeen, Md. Habib Ullah Masum A Reverse Vaccinology Approach for the Design of Dual mRNA Vaccines: Targeting Measles Antigens and Conserved Sequences from Measles, Mumps, and Rubella Viruses Using Molecular Docking, Dynamics and Immune Simulations
   Conference name: 3rd ICALS Conference 2025.

Research Grants

• National Science and Technology (NST) Fellowship 2023-2024, in Biological and Medical Science by Ministry of Science and Technology, Bangladesh.
• Teacher Student Joint Research Grant (2023) awarded by Research Cell, NSTU

Awards and Grants

• Best presenter award: Winner of the ISBM Annual International e-Conference 2025.
• Merit Scholarship: Tuition fee waiver in the 3 (out of 8) semesters of undergrade for securing place in top three, by Noakhali Science and Technology University.

Skills

Computer: SPSS (Statistical data analysis), Biorender, Microsoft office, Adobe Photoshop and Illustrator, Canva, Emailing & Internet browsing.

Bioinformatics: Cancer Biomarker Analysis (GEPIA2, GENT2, UCSC XENA, ONCOMINE, UALCAN, Cbiportal, PrognoScan, STRING), Gene Therapy (I-SCORE, DSIR, REYNOLDS, AMARZGUIOUI), Epitope Prediction and Population coverage analysis (IEDB Analysis Resource), Molecular Docking (Clustpro, Autodock Vina, H-DOCK, Patch DOCK, HawkDock,, CABS-dock), Molecular Dynamic Simulation (GROMACS, DESMOND), Tertiary Structure Prediction of protein (AlphaFold, I-TASSER, Raptor X), MM-GBSA (HawkDock), Disulfide Engineering (Disulfide by Design), Immune Response Simulation (C-IMMSIM), Codon optimization (Jcat), In-silico Cloning, In-silico PCR and In-Silico Gel Electrophoresis (SnapGene), mRNA structure prediction of protein (RNAfold, RNAcofold), biological pathway analysis (Cytoscape, EnriChr, DAVID)

Analytical: Geographic Information Systems (GIS), R programming, Python programming.

Laboratory: Culturing Microorganism, ATCC handling and culture, Biochemical Test, DNA Extraction, PCR, qPCR, RT-PCR, Gel Electrophoresis, Biofilm Formation Assay (tube, congo red and tissue plate), Metal Susceptibility Test, Antibiotic Susceptibility Test, Nanoparticles Susceptibility Test etc.

Research: Writing Original and Review Article, Endnote and Mendeley Citation.

Language: Bengali, English.

Training and Certifications

• 2020 – Immunoinformatic and Vaccinomics (BIOSOL Center)
• 2021 – Multiple Coursera Certifications (Stem Cells, Oncology, Astrobiology, Epidemiology, etc.) from Johns Hopkins, University of Edinburgh, University of Arizona, etc.
• 2021 – Detecting COVID-19 with Chest X-Ray using PyTorch (Coursera Project)
• 2021 – DNA Decoded (McMaster University)

Extracurricular activities

• Demonstrated leadership skills by serving as a Class Representative till Post-graduation (6 years) (2018-2024)
• Trainee at Globe Biopharmaceuticals (August 2022-September 2022)
• Collaborated with faculty and students to address academic concerns and improve the learning environment
• 2nd Position holder at Essay Competition organized by “Agnishikha” (2012)
• Representative of a day-long advanced workshop entitled “Career Essentials 2k19” organized by Bishwobiddaloy.com (2019)