The Congregation Holy Cross was founded by Blessed Basil Anthony Moreau in Le Mans, France, in 1837. In Latin the name of the group is Congregatio a Sancta Cruce (CSC).  The Congregation, composed of two Societies of religious priests and religious brothers, has more than 1200 members and is currently serving in sixteen countries on five continents.  Notre Dame University Bangladesh was established in 2014 by the Holy Cross Fathers of the Sacred Heart of Jesus Province. 

The Congregation first came to serve in East Bengal (now Bangladesh) in 1853. Since then the CSC priests, brothers and sisters have established primary schools, high schools, and colleges in  remote areas as well as in the cities and towns of this country. NDUB is the first Catholic university and the first Holy Cross institute of higher education to be established in Bangladesh.